Drama · Horror · Thriller
The Strain is a high-concept thriller that tells the story of Dr. Ephraim Goodweather, the head of the Center for Disease Control Canary Team in New York City. He and his team are called upon to investigate a mysterious viral outbreak with hallmarks of an ancient and evil strain of vampirism. As the strain spreads, Goodweather, his team, and an assembly of everyday New Yorkers wage war for the fate of humanity itself.
46 listed episodes across 4 seasons. Air dates are provided by TVmaze and can change.
When a plane lands in New York City with everyone on board dead, Dr. Ephraim 'Eph' Goodweather, head of the CDC's Canary Project, and his team are called upon to investigate. What looks at first like a mysterious viral outbreak might be the beginning of something infinitely more sinister
The four survivors begin manifesting strange symptoms, but Eph and Nora's attempt to quarantine them is thwarted as the disinformation campaign begins. Setrakian receives a surprise visit from an old – a very old – acquaintance.
Eph and Nora fight to save Captain Redfern's life before coming face-to-face with the horrifying effects of the virus. A spike in rat attacks signals Fet that something inexplicable is happening deep below the city. Released from jail, Setrakian begins his own merciless plan to stop the spread of the disease.
A secret autopsy demonstrates the bizarre progression of the mystery virus, prompting Jim to make a startling confession. Eph and Nora race to find the father of the youngest victim of the plane tragedy, but someone unexpected beats them to it. Ansel, in the grip of disease, takes desperate measures to protect his family.
With Nora gone, Eph reluctantly joins Setrakian's quest in hopes of gathering enough evidence to warrant a citywide quarantine. Fet encounters the unexpected inside the subway tunnels. A medical emergency threatens Palmer's master plan.
After warning Kelly to leave the city with Zack ahead of the spreading plague, Eph is arrested by the FBI. Eichhorst has one final job for Gus. Setrakian realizes that the coming eclipse is the tipping point for virus infection and the beginning of the end
Setrakian, Eph and Nora formulate a plan to track down the Master using Jim as bait. Eichhorst and Setrakian's pasts are revealed. At the Luss home, Neeva struggles to protect the children while encountering a mysterious stranger whose help she may not want.
After discovering the potency of ultraviolet light against the strigoi, Setrakian gains a new and unlikely disciple. A quick trip to a Brooklyn convenience store turns into a deadly all-night siege.
Eph races to safeguard his family, only to learn that Kelly is missing. Dutch reveals her role in Palmer's plan. Gus is forced to make a difficult decision about Felix.
Eph investigates Kelly's disappearance and struggles with what he finds. Dutch pursues a plan to retaliate against Palmer. Fitzwilliam makes a surprising choice.
Setrakian leads Eph, Fet and Nora in the hunt for the Master's lair. Left behind at the pawnshop with Mariela, Zack risks his safety for Mariela's sake.
Dutch returns with a plan to broadcast Eph's warning about the vampiric plague, but they face a new threat when Eichhorst launches his own attack against the pawn shop. Palmer receives a special visitor. Gus gears up for the on-coming fight but discovers there's another mysterious factor involved.
Eph and Fet recon for an all-out assault that Setrakian assures them will finally kill the Master. Gus aligns himself with a strange new force, one that may swing the fight in an unforeseen direction.
Setrakian risks the lives of the entire group to find information about a closely guarded secret text. The Master begins the next phase of his own plan by creating a terrifying new breed of creature and placing them under Kelly's control.
Eph and Nora experiment on their newfound patients. Fet and Dutch grow closer as they clear out the neighborhood buildings, and Kelly begins her hunt for Zack.
Gus and Vaun wage an attack on Palmer as Eph struggles to connect with Zack. Councilwoman Justine Faraldo vows to bring her extermination policies to the other boroughs.
Eph and Nora finally see their lethal virus in action. Fet takes the security of Red Hook into his own hands while Dutch and Setrakian set off for Staten Island to question Fitzwilliam, Palmer's former bodyguard.
Eph changes his appearance to leave the city while Nora is left as the reluctant parent for Zack. Dutch and Nora make a deal with Justine to secure Fet's release from jail.
Eph concocts a plan to make and distribute a bioweapon. Gus realizes Angel can be an unlikely ally, and Kelly comes after Nora and Zack.
Setrakian and Fet use Fitzwilliam's info to attack the Master, but a mysterious new player arrives. Dutch receives a surprise guest. Eph returns to NYC frustrated but energized to go after the one person responsible for killing his friends.
Eph must protect Zack against a surprise intruder into Red Hook. Gus convinces the Guptas to make a difficult choice. Fet and Setrakian set out to acquire the Lumen but discover they are not the only potential buyer.
Justine takes drastic measures to counter a surprise invasion. Nora and Fet perform a useful mission while Eph and Setrakian face off against an old foe.
Dutch helps Eph attempt to assassinate Eldritch. Meanwhile, Abraham, Vasiliy, and Nora search for Rudyard Fonescu and the Lumen, while Justine tells the Upper East Siders the price they have to pay for her help.
Eichhorst relives his past while torturing Dutch in the present, while Vasiliy and the others try to find their friend. Meanwhile, Abraham finally meets Rudyard, and Gus and Angel take the Guptas to safety.
Eph makes arrangements to get the bioweapon to Justine, in return for travel permits to get Zack to his grandparents. Meanwhile, Eichhorst warns Eldritch that the white's effects are temporary, and Gus and Angel travel to Rikers to get a new attack squad for Quinlan.
While Eph and Nora take Zack to the boy's grandparents, Abraham and Vasiliy prepare to bid for the Lumen against Eichhorst. Meanwhile, Quinlan and his Day-Hunters make their move.
Vasiliy aids Navy SEALs trying to track down the Master, while Abraham and Quinlan try to translate the Lumen. Meanwhile, Eph returns to his home in the hopes that Zack will somehow make his way there, but Kelly arrives to make Eph an offer.
Eph approaches Abraham to find out what the Lumen tells about the Master's weaknesses, and Quinlan suspects treachery. Meanwhile, Kelly tends to her captive son and arranges his introduction to the Master. And a desperate Eldritch offers Abraham a deal in return for the secret of the white.
Eph helps Quinlan steal the Lumen to draw the Master out. While Abraham and Vasiliy close in on their prey, Quinlan reviews how he came to be. Meanwhile, Gus convinces Angel to help him get Guadalupe to safety.
Quinlan and Abraham realize that the Master still lives as long as his essence is at large. Meanwhile, Eichhorst takes control of the strigoi and launches a new attack on Justine and the NYC command structure.
While Abraham and Quinlan search the Lumen for a way to defeat the Master, Abraham recalls his encounter with another strigoi in Amsterdam in 1972. Meanwhile, Eph and Dutch try to find a way to stop the strigoi from communicating, and Vasiliy discovers the new plan that the creatures are up to.
Justine and her people launch a desperate attack on the strigoi nest below Central Park. Vasiliy takes an insertion team in, while the city has the convict teams sweep the tunnels. Meanwhile, Dutch and Eph try to hack the strigoi communication network, and discover that Zack is still alive.
Vasiliy checks on his parents and makes a startling discovery. Meanwhile, Eph and Dutch convince Quinlan to accompany them on a trip to JFK to recover the black box from the Master's flight.
Abraham and Vasiliy continue their hunt for the Old World Ancient. Meanwhile, Quinlan tells the Ancients about Abraham's plan, and Eph is forced to nurse Dutch back to health after her exposure to the Master's voice.
With the strigoi ready to overrun the city, Vasiliy warns Dutch and Eph to get out. Meanwhile, Gus and Angel try to leave the city but run into Justine, and Eichhorst tracks down the cargo from the Aurora Cutlass.
It's the final showdown as the team tries to capture the Master and place him in the box. However, the fate of humanity lies in one boy's hands.
Nine months after the warhead detonated in New York, the strigoi have formed a "partnership" with the humans, offering free medical care in return for blood donations. Eph is in Philadelphia trying to make a life for himself on the fringes, while Vasily and Quinlan try to acquire a nuclear warhead. Meanwhile, the Master plans to raise Zack as his next host body.
The fates of Gus and Dutch are revealed, while Eph continues to help Alex and her brother.
While Vasiliy and Quinlan try to obtain a nuclear warhead, Eph leads a strike against the strigoi in Philadelphia... alerting the Master and Eichhorst to his presence. Meanwhile, Zack makes a new friend.
Desai forces Dutch to help him calm down a woman undergoing C-section. Meanwhile, the underground takes a heavy blow and Eph and Alex learn of New Horizons.
While Vasiliy and Quinlan acquire the nuclear pit from the strigoi convoy, Eph and Alex head for New Horizons to discover it's secret. Meanwhile, Dutch leads a rebellion and finds Abraham, while in the past, Quinlan finds a moment of happiness.
Roman takes the others to meet with an old friend who can provide them with a plane and get the warhead to New York. Meanwhile, Zack learns a painful lesson about love.
Eph reunites with Abraham and Dutch, bringing Alex along with him. His health failing, Setrakian ignores Eph's warnings, pushing himself to the limit in his quest for victory and revenge. Fet and Quinlan race back to Manhattan. Meanwhile, Gus decides to help the resistance, but Creem goes to the Master with valuable information. Later, the Master seals off the city and prepares to eliminate them all.
Before he has Quinlan kill him, Abraham tells the others how to defeat the Master. They begin by assaulting the Partnership facility and capturing Desai. Meanwhile, the Master sends Zack on a special mission.
The team threatens Selah to get leverage against Desai. Meanwhile, Eph tries to determine if Zack is working for the Master or not, while Gus goes to recover the nuke.
The team is forced to retreat, and Quinlan and Vasily come up with a plan to use the nuke to destroy the Master once and for all.
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